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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c374bcf64c3af04bf1843b3ab6bfafa9a788c8876d48d7006b8be637b88b3164' 
  AND token = 'jnordCgMugzpsbvCZlc1TZ2tDp6K3AN1V4cAMod9CDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}