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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '807e55297a20ce8d0458f062e822c2290657bc109b040a3c9b00c6e493950b91' 
  AND token = 'tL0B8PjIJJiksRHDfXOeDY8oWsmyui9nN21xItZMKWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}