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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '758eeb3a04f0c9c7f962d4e10027378c83f86d3ca6302eeea18420378472135b' 
  AND token = 'X6dMQC4vK1D6q3/yxaymdaRL1zIhcw6uB3sFEqjCgd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}