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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ab87d77a3daf5d5d8896fc8c94b27227a9614be89f701566180ea5ebe0e8df0' 
  AND token = 'uu/uz++9x06MCIJ++wZWif50yzbF8sQEAmdKLGve0Sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}