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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '183af7e8cac24c31941c476d7e853dc9b06e0cd994c9140695ca44a7837f2bbd' 
  AND token = 'cKsgrmM8vakk2Z+hFUFZ3ltMOM795e7lh0Z+xmm1DIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}