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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7366cd371e6c79fb8c618a0566c89aa5bdba706c506800ef371dbfc1eef1df9e' 
  AND token = 'hGT2uZ4vEHm+oqM3g2IEf3Rn7rZG+4xyQCqp6D1+HuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}