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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da6a43d6d9f1b9176864fb96af384cdde20ecca5bdc95e39de44cf98591e6ec0' 
  AND token = 'wT7w/M+lHi+P5oUNVB/y8YrcA4uUprMzyCSYiuoJQNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}