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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48ec4b7d04aa749d0ea4329ed2f8bf7292373c145eb3d822e6e66881d593a671' 
  AND token = '1bsTCL/35EnjIEFmTxaw6aeVm6x/sscHOy1EMt7ZX34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}