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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '005e772f2f105827a8f13b0447a03d4987b77f6cf13240f8a100bece2fc8e693' 
  AND token = 'LrdEhEjTCI7/Mlk1Fl8GKW5CO5UCvM5zHRAgfuOu7p4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}