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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d43862fb9b787ea68e39cacbb4e95620891de6f1591fde9c0a59b54d0a9ee2d' 
  AND token = 'FBONSlv7MbiITYt5PPcZjxKr+xeNUrJV1bH3paOCmi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}