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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee4938ef8150ebd8e6000dd2aa761aed04aa74c5e20971232147a33dd6f2dca4' 
  AND token = 'yNYMe7FC7k8zUx4u+WdQf8hrihuBrqJFtgSoBTZMgFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}