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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd52b1eba24c62a37e309abfa378b88baf092f4df152adee564e7fb4bf4d033f' 
  AND token = 'LiFJBMg7N5tjoc07ER8jrtTJOh+o/E3gxkWkiSIbC2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}