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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '655b8b36ef55c1b610beac798f338419137ef0c60a3270ba869487a7b63b0299' 
  AND token = 'n1SwZs4idc5u8/fOAtDdd9Fnu9nCr2gLNsXYCwTs22I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}