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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb4e1b49dcd1a6bb7f72df64f0dcc36a12afc726f453f6be9d24591bee6a1acc' 
  AND token = '9XczIYk4nU1GJ6VD7OxBD/9APCpz8va5rIZ8CpaZVDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}