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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd649db5ba5871de07d85acfb9e1f49721e86fcc3b21a052c7ba0a6055294583c' 
  AND token = 'MTLzAiG12yctd1+ro1ecY6arQPECLUMqCjS7JGBEq/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}