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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00b3e70c21da726717074581229eb4e951475c6feb5c38d16ba06f01b1114194' 
  AND token = 'XUWV7OIRstxmVOqdJNKAEW6D7iuYshIgXHXaGKMOz74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}