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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81c49962b8f912688661a030ecaf064ac64e46a8f25db3059fe232dd04876a66' 
  AND token = '2EKoAtKSo2PzuR0vpMYaE9vu/+VywTOaUUChRmF91nQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}