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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa54f37990deb94aac99f27cfc216af763f2f70be07e8f22f60d7648e96c81e2' 
  AND token = 'BByC3pmCsVWayiyYsm6TX6czTsVEdhMbP3uRpDwSWGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}