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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be2890b440b40f6ed2f5544fbefc5cbe7f4fde445fcf3fa25f3f70c122dedd22' 
  AND token = 'oA4MPJ+wTYdvHiBlCQgDKmayqYR6AQ8+I0SuHxTHXEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}