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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0fb963fb2f385e5d13847750fe2da76b48883697d33b4e829c05312f77c34b8' 
  AND token = 'KBgL6ne32fTFLJ5K/QfseCgUqRy+tXnPAkIIN51i1XY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}