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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33ac4a6f7f162f20aa92ba2c7effac47fb44c5976133d4433120560b2c2bbc0e' 
  AND token = 'ay2vAA6AzD3hsfdv5ZuAVFxSh/xkCnggUVbf1AEXEnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}