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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c2f2dc2f393faa910b63d91012110a79f4104908b611ff164886a64680c8e5b' 
  AND token = 'c1h4Wq2Qg6dE5Jt0V07PErZNNzoVSr6CGiuT0KUWFPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}