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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0887ff53b037c9884cd6994a414e34c2c065d919874301d47ff0157cc103c02' 
  AND token = 'YlSZHd2Ce4cGRqVgpI/F0Wv+EEK0RRgCqcq/4ReuY64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}