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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '273a4d90abc9b2a28d60b0dcbfac6bbbd01093f662be1ff37447c6530edbf73f' 
  AND token = 'rnb6+JHV1fZzHg3YyJIMNkV6y0a3cuaDtv0rnUSie0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}