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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06fa44186608ac1dc67ee87fb2bb2bf100020bf0bc06cff6e5d5597a7a9ea645' 
  AND token = 'wHXxSZhNOB+nhTTpa5gmWhgs4wEHsJH2FdRN3CG0cG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}