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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46506da1b4c8372c22c1ea9a4e3ffc9e03a13c106105375d9eefae437ea525c3' 
  AND token = 'R4ov7u9ooHR+U4+MGKAk5yMaV2mS5Q7FJLX4e0Vk0b8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}