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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a81e2ddc77b22fe8144f240d9fbfebb57c0553e2278331b06620a784108a504' 
  AND token = 'maUoF/fJNnn6NKWyp7X5LT410uEEP8Eao3KqHSvqq9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}