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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24c000ccb00de75cd611924a91d9e3a48773bc65f157c3fd6049669e5d95b01f' 
  AND token = 'PcpU+mkvG6rimf7+3tE7s/NqOuKC5PMH5zsUDWQpi+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}