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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1f30c09f89e2e9ba2f97b996276282d19c149225a7462ef9b6ec7463c678bdc' 
  AND token = 'U3fkZTF0+W9Cx5mEVNYMezz+qVSPJpL4MM+A0AQgEso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}