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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab66d526060edbfa30f22c984063ec037941b27ef8b1d21ee531e5e802862178' 
  AND token = 'i+n2v38a2pOaInC4dWynzhAOedX8GcN6bqcGMa5rzug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}