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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a39c9faf7c4516e0f6ede9f7f469b9f0188392bc9257837d88bb3a889b14dd44' 
  AND token = 'H2tU6ioQ0kb7vGq+NI2bAg9uHi44IgQsQsRKYOc0OrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}