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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05319219f71c017b5ae0a2b60ae1de78510f09f8e7e7a421371a15e8590df826' 
  AND token = 'sQ7cwhoVOW/UGiMo3QsyzKa4/4vdKAYzpZF3cbu/8bU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}