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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45716445c1af072f2022b61825c821452dad1408a26f7e0aa4a592d6d06b8e36' 
  AND token = 'YmCkw1Y8TZWoWb4pnIYI3CmK7MTUAJi3g++vbWcBlG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}