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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ad8508dbfc544cfdefd278c287853a86b2d5605beb95918381602e44abb68c2' 
  AND token = '+StMkL0lADhKhDrPLZXJj6f9JFEGn7gucIk0t4dv5Vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}