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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86503c32b87e882eb21001b2aeda257b2d4da654067df4f6a1811783e1a04224' 
  AND token = 'G321uwTQGgA5XUy6s0Sc3C6BOzodqkkDvWHKG5DzOKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}