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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b100f1b34cc287dc61f1fc21d0d8d1b184233b3fbec4870ae199610c63f51568' 
  AND token = '8uQVlHq6v4gA0e8lfSJyMULM7kdBEEyKCF+E9QBOclw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}