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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff48adc9edc1175929caa7d30f1530af3b06cd220e12a2fd9805df4bb8e50f2d' 
  AND token = '2fp1ATTbk+GM5Bow7HNslqkSpFbfPNW5T3vXSqL/IRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}