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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e48787050528976c3cf1a6d5dea3322555743e69e4f0c76983bd9deb500acc2' 
  AND token = '8Q1gSS1CmbevQQYkIZpK7hJAHREFQRjaLGY2MeL/FJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}