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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56105652441fee62dae2bf4668a0bb00041dd41a0a2115a2d253d7374b88e335' 
  AND token = 'WpoREKwis0gHTnGT8WM/dE81bcFLC7gTh3VHlBXcyjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}