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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f096405852d10d0c8c6ec8ea8b9b036740b22b582217b1d5fa3430c5649ce63f' 
  AND token = '2CUW8V3S0N59F+0ONpkK26i+nA/RigZjVkh/l+UXNMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}