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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ed4a13cc6eb05d32cfb2f53fd2dd76ebb4ca785a22980402390dfec5b1c1776' 
  AND token = 'arf35F1MYPxCMg9pXaM/oiKLwHecRxj8rzZxtyvIBLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}