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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '581e7381ab26cca76868c9179fc9dccf1f903b165096273aa7c2ef111e1f4a7f' 
  AND token = '4SxGA1CZAyEJPK/0vOCjsmSG1MYj26QHbI7YQD5Aom0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}