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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01dfa89ea3937389e5eac1a6e0f69efe6d82e197aad85dc2b4d518f03785d288' 
  AND token = 'kKhy5rOkVZbwX8/udjMU5AdJbg8T22WrJL1CExsVC18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}