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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b0429e22f4e233b50bc779dd535f717fbac5af157c2f92df6dfdcae34dcf030' 
  AND token = 'cMckIsn2+1VLHVrADMPnDdYmkWLs3LC2VITaSxAXDGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}