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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ca215edbdf557b4d86da1b2f244a118e983dfade0e5c7ef776a15faf666520a' 
  AND token = 'NGWFEAgFTuUjiw44N/11dBK4uI0GdfMkIgbGkvMNux8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}