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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b9933487fc3d5199a03a98930f0519b459def5d9ff41e5901b2116f52e4c11f' 
  AND token = 'XQ1bGsSZ7daIHpGn/VKDL9atOpBSKp3hx8hYHOuOM7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}