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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f75a5502d011d06be116d3afdfd1fc550402241b15b80a78d0f71ee4287714' 
  AND token = 'zwy3QJRCnO7K6DUJxJWHsMRh4yvl+JaZHcRK5xsAl+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00194

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}