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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46dd0c208b723ce095a4056dcd9a7939512c440f7f3c204a4156d45f39131084' 
  AND token = 'GHV/NaL0kqhXMo1ky+qiCrKzN/VdFact69jUWkuuQkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}