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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c78a5a991ff76304dacabb355b7fb7f2420b717eb421947a4b7aa24727c47b9' 
  AND token = '0aNe6Y91loMP/GKeE1mPiyvx6BaCwMzRJ8NKK9qjDEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}