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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ebb3d9417a7e1276c7410c4ba2deb21cebb072e6a16782dfa4d1c60e0b6e360' 
  AND token = 'GMPFpGF0qJjmt1zr1hQWmYF2KUwC8seGj4rXW0swZPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}